經顱直流電刺激(tDCS)一種非侵入性的利用恒定、低強度直流電進行神經調節的技術,其通過電極將電流輸送到特定的腦區,目前用于某些疾病研究:中風后康復,疼痛,帕金森,癲癇,阿茲海默,抑郁,精神分裂等,而在健康被試者身上的試驗已經表明其可用于認知提高,比如提高語言、記憶、數學、注意力、協調等研究。
美國Activa公司出品的tDCS產品因其方便、便宜、易操作的特點被新墨西哥大學Vince Clark教授(tDCS科研奠基人之一,neuroimage編委)選作指定的研究工具。
Activa產品已經被多個實驗室使用,發表數百篇科研文獻,完全是科研級別的設備,由于其價格非常低廉,您無需申請大量科研經費即可購買全套tDCS設備,立即開展科研實驗;蛘咄瑫r準備多臺進行群體實驗。
產品特點:
1.雙通道,雙可調節旋鈕,用于調節電流強度及時間;
2.高清顯示刺激劑量:電流強度、刺激時間;
3.刺激量足;
4.刺激劑量達到最多每分鐘80mA;
5.擁有阻抗測試功能,在電極阻抗較高時自動給予
視覺、聽覺報警;并自動限制電流及中斷刺激;
6.自動計算刺激時間,并在刺激中斷后進行重新計算;
tDCS套件包含:
1.刺激器主機一個;
2.正負極導線一對;
3.夾貼式導線一對;
4.一對電極(2x2或3x3)
5.2節9伏堿性電池;
6.10片可替換電極
選配件:
紐扣電極 碳纖維電極 口袋電極 針狀電極導線 鹽水海綿電極
使用Activa(PM850)產品發表文獻節選:
1. Baker JM, Rorden C, Fridriksson J. Usingtranscranial
direct-current stimulation to treat stroke patients with aphasia.
Stroke. 2010;41(6):1229-36.
2. BenningerDH, Lomarev M, Lopez G, Pal N, Luckenbaugh DA,
Hallett M. Transcranial directcurrent stimulation for the treatment of
focal hand dystonia. Movement Disorders. 2011;26(9):1698-702.
3. BenningerDH, Lomarev M, Lopez G, Wassermann EM, Li X,
Considine E, et al. Transcranialdirect current stimulation for the
treatment of Parkinson's disease. Journal of Neurology, Neurosurgery
& Psychiatry.2010;81(10):1105-11.
4. BorckardtJJ, Bikson M, Frohman H, Reeves ST, Datta A, Bansal
V, et al. A pilot study ofthe tolerability and effects of
high-definition transcranial direct currentstimulation (HD-tDCS) on pain
perception. The Journalof Pain. 2012;13(2):112-20.
5. BradnamLV, Stinear CM, Barber PA, Byblow WD. Contralesional
hemisphere control of theproximal paretic upper limb following stroke.
CerebralCortex. 2012;22(11):2662-71.
6. CantareroG, Spampinato D, Reis J, Ajagbe L, Thompson T,
Kulkarni K, et al. Cerebellardirect current stimulation enhances on-line
motor skill acquisition through aneffect on accuracy. The Journal of
Neuroscience.2015;35(7):3285-90.
7. CantareroG, Tang B, O'Malley R, Salas R, Celnik P. Motor
learning interference isproportional to occlusion of LTP-like
plasticity. TheJournal of Neuroscience. 2013;33(11):4634-41.
8. CelnikP, Paik N-J, Vandermeeren Y, Dimyan M, Cohen LG.
Effects of combined peripheralnerve stimulation and brain polarization
on performance of a motor sequencetask after chronic stroke.
Stroke.2009;40(5):1764-71.
9. CerrutiC, Schlaug G. Anodal transcranial direct current
stimulation of the prefrontalcortex enhances complex verbal associative
thought.Journal of Cognitive Neuroscience. 2009;21(10):1980-7.
10. Clark VP,Coffman BA, Mayer AR, Weisend MP, Lane TD, Calhoun VD,
et al. TDCS guided usingfMRI significantly accelerates learning to
identify concealed objects. Neuroimage. 2012;59(1):117-28.
11. Clarke PJ,Browning M, Hammond G, Notebaert L, MacLeod C. The
causal role of thedorsolateral prefrontal cortex in the modification of
attentional bias: Evidencefrom transcranial direct current stimulation.
Biologicalpsychiatry. 2014;76(12):946-52.
12. Galea JM,Vazquez A, Pasricha N, de Xivry J-JO, Celnik P.
Dissociating the roles of thecerebellum and motor cortex during adaptive
learning: the motor cortex retainswhat the cerebellum learns. Cerebral
Cortex.2011;21(8):1761-70.
13. GoldmanRL, Borckardt JJ, Frohman HA, O’Neil PM, Madan A,
Campbell LK, et al.Prefrontal cortex transcranial direct current
stimulation (tDCS) temporarilyreduces food cravings and increases the
self-reported ability to resist food inadults with frequent food
craving. Appetite.2011;56(3):741-6.
14. Halko M,Datta A, Plow E, Scaturro J, Bikson M, Merabet LB.
Neuroplastic changesfollowing rehabilitative training correlate with
regional electrical fieldinduced with tDCS.
Neuroimage.2011;57(3):885-91.
15. Hamner J,Villamar MF, Fregni F, Taylor JA. Transcranial direct
current stimulation(tDCS) and the cardiovascular responses to acute pain
in humans. Clinical Neurophysiology. 2015;126(5):1039-46.
16. Hummel F,Celnik P, Giraux P, Floel A, Wu W-H, Gerloff C, et al.
Effects of non-invasivecortical stimulation on skilled motor function
in chronic stroke. Brain. 2005;128(3):490-9.
17. Hummel F,Cohen LG. Improvement of motor function with
noninvasive cortical stimulationin a patient with chronic stroke.
Neurorehabilitationand neural repair. 2005;19(1):14-9.
18. Hummel FC,Heise K, Celnik P, Floel A, Gerloff C, Cohen LG.
Facilitating skilled righthand motor function in older subjects by
anodal polarization over the leftprimary motor cortex. Neurobiology of
aging.2010;31(12):2160-8.
19. Iyer M,Mattu U, Grafman J, Lomarev M, Sato S, Wassermann E.
Safety and cognitiveeffect of frontal DC brain polarization in healthy
individuals. Neurology. 2005;64(5):872-5.
20. Jayaram G,Tang B, Pallegadda R, Vasudevan EV, Celnik P, Bastian
A. Modulating locomotoradaptation with cerebellar stimulation. Journal
of neurophysiology.2012;107(11):2950-7.
21. Koo YS,Kim SM, Lee C, Lee BU, Moon YJ, Cho YW, et al.
Transcranial direct currentstimulation on primary sensorimotor area has
no effect in patients withdrug-naïve restless legs syndrome: a
proof-of-concept clinical trial. Sleep medicine. 2015;16(2):280-7.
22. Kwon YH,Kang KW, Son SM, Lee NK. Is effect of transcranial
direct current stimulationon visuomotor coordination dependent on task
difficulty? Neural regeneration research. 2015;10(3):463.
23. LindenbergR, Renga V, Zhu L, Nair D, Schlaug G. Bihemispheric
brain stimulationfacilitates motor recovery in chronic stroke patients.
Neurology.2010;75(24):2176-84.
24. LindenbergR, Zhu LL, Rüber T, Schlaug G. Predicting functional
motor potential in chronicstroke patients using diffusion tensor
imaging. Humanbrain mapping. 2012;33(5):1040-51.
25. LindenbergR, Zhu LL, Schlaug G. Combined Central and Peripheral
Stimulation to FacilitateMotor Recovery After Stroke The Effect of
Number of Sessions on Outcome. Neurorehabilitation and neural
repair.2012;26(5):479-83.
26. McCambridgeAB, Bradnam LV, Stinear CM, Byblow WD. Cathodal
transcranial direct currentstimulation of the primary motor cortex
improves selective muscle activation inthe ipsilateral arm. Journal of
neurophysiology.2011;105(6):2937-42.
27. McCambridgeAB, Stinear JW, Byblow WD. A dissociation between
propriospinal facilitationand inhibition after bilateral transcranial
direct current stimulation. Journal of neurophysiology.
2014;111(11):2187-95.
28. RassovskyY, Dunn W, Wynn J, Wu AD, Iacoboni M, Hellemann G, et
al. The effect oftranscranial direct current stimulation on social
cognition in schizophrenia: Apreliminary study. Schizophrenia
research.2015;165(2):171-4.
29. ReidlerJS, Mendonca ME, Santana MB, Wang X, Lenkinski R, Motta
AF, et al. Effects ofmotor cortex modulation and descending inhibitory
systems on pain thresholds inhealthy subjects. The Journal of
Pain.2012;13(5):450-8.
30. Reis J,Schambra HM, Cohen LG, Buch ER, Fritsch B, Zarahn E, et
al. Noninvasivecortical stimulation enhances motor skill acquisition
over multiple daysthrough an effect on consolidation. Proceedings of
theNational Academy of Sciences. 2009;106(5):1590-5.
31. RushmoreR, DeSimone C, Valero‐Cabré A. Multiple sessions of
transcranial direct currentstimulation to the intact hemisphere improves
visual function after unilateralablation of visual cortex. European
Journal ofNeuroscience. 2013;38(12):3799-807.
32. SalimpourY, Shadmehr R. Motor costs and the coordination of the two arms. The Journal of Neuroscience. 2014;34(5):1806-18.
33. ShahbabaieA, Golesorkhi M, Zamanian B, Ebrahimpoor M, Keshvari
F, Nejati V, et al. Statedependent effect of transcranial direct current
stimulation (tDCS) onmethamphetamine craving. International Journal
ofNeuropsychopharmacology. 2014;17(10):1591-8.
34. SoekadarSR, Witkowski M, Birbaumer N, Cohen LG. Enhancing
Hebbian learning to controlbrain oscillatory activity. Cerebral
Cortex.2015;25(9):2409-15.
35. Vines BW,Cerruti C, Schlaug G. Dual-hemisphere tDCS facilitates
greater improvements forhealthy subjects' non-dominant hand compared to
uni-hemisphere stimulation. BMC neuroscience. 2008;9(1):103.
36. Yoon EJ,Kim YK, Kim H-R, Kim SE, Lee Y, Shin HI. Transcranial
Direct CurrentStimulation to Lessen Neuropathic Pain After Spinal Cord
Injury A MechanisticPET Study. Neurorehabilitation and neural
repair.2013:1545968313507632.
37. You DS,Kim D-Y, Chun MH, Jung SE, Park SJ. Cathodal
transcranial direct currentstimulation of the right Wernicke’s area
improves comprehension in subacutestroke patients. Brain and
language.2011;119(1):1-5.
購買聯系及技術支持:楊經理 電話:18580429226 QQ:914622680 |